Does timolol affect breathing?
Does timolol affect breathing?
Timolol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, swelling of the face, fingers, feet, or lower legs, weight gain, or trouble breathing.
Can eye drops affect your breathing?
Systemic absorption of /3-antagonist eye drops can cause unsuspected respiratory impairment. Physicians should be alert to the possibility of respiratory side-effects of topical therapy with /3-antagonists and whenever such side-effects occur should use alternative treatments.
Can timolol eye drops cause shortness of breath?
dorzolamide and timolol ophthalmic can cause serious breathing problems or heart failure. Get medical help if you have shortness of breath, pounding heartbeats, swelling in your lower legs, or rapid weight gain.
Does timolol trigger asthma?
In a provocation test, fifteen minutes after application of timolol, wheeze and dyspnea were induced following an increase in respiratory resistance. After the asthma attack, transient hypoxemia, bradycardia and decrease in blood pressure were also observed.
Does timolol cause asthma attacks?
Abstract. The inadvertent administration of timolol to asthmatic patients continues to cause occasional severe and even fatal attacks of asthma. The (R)-enantiomer of timolol, L-714,465, is four times less potent than timolol in reducing intraocular pressure in man. It is 49 times less potent than timolol on beta 2-adrenoceptors in animals…
What are the side effects of Timolol eye drops?
Although the risk of serious side effects is low when timolol is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream. Call your doctor right away if you have: numbness or cold feeling in your hands and feet. eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection); or
Should timolol ophthalmic eyedrops be used in bronchospastic patients?
It is not generally appreciated, however, that timolol ophthalmic eyedrops should be used with caution or even avoided in patients with bronchospastic disease. [1]
Is there a safer alternative to timolol for the treatment of glaucoma?
Abstract. It is 49 times less potent than timolol on beta 2-adrenoceptors in animals and 13 times less potent on the airways of normal subjects. These findings suggested that L-714,465 might be a safer alternative for the treatment of glaucoma. 2. Ten subjects with mild asthma who bronchoconstricted to timolol eye drops (0.25 or 0.5%) were studied.