What is schedule for TWINRIX vaccine?

Twinrix was first licensed by FDA in 2001 on a 3-dose schedule (0, 1, and 6 months) for vaccination of persons aged >18 years (1). Using the newly licensed, alternate 4-dose schedule, Twinrix doses can be administered at 0, 7, and 21–30 days, followed by a dose at 12 months.

How long should I wait between doses of TWINRIX?

TWINRIX dosing schedules. Standard TWINRIX dosing is 3 vaccine doses over a span of 6 months. You choose the date for the first dose. The second dose is 1 month after the first and the last dose is 6 months after the first. A 4-dose rapid schedule is also available for adults 19 years and older.

What are the minimum intervals between hepatitis B vaccine 1st and 2nd doses and 2nd and 3rd doses for adults?

*The schedule for hepatitis B is flexible, but minimal intervals and minimum ages need to be observed: There should be at least 4 weeks between doses 1 and 2, and at least 8 weeks between doses 2 and 3. The minimum interval for the overall series from dose 1 to final dose is 4 months (16 weeks).

How many doses of TWINRIX are required for adults?

A dose of 1.0 ml is recommended for adults and adolescents 16 years of age and above. The standard primary course of vaccination with Twinrix Adult consists of three doses, the first administered at the elected date, the second one month later and the third six months after the first dose.

How effective is TWINRIX after 2 doses?

The Twinrix® 19 yrs of age and older / Twinrix® Junior dosing schedule involves boosters at 1 and 6 months after the first dose; over 95% of people are protected against hepatitis A & B one month after the second dose.

Do I need a booster for TWINRIX?

Will I need a booster dose? For long-term protection against hepatitis A and B, you must complete all your scheduled TWINRIX doses. The standard dosing schedule (3 doses) requires the third dose 6 months after the administration of the first dose.

What if I miss my second Hep B vaccine?

If you miss a dose or get behind schedule, get the next dose as soon as you can. There is no need to start over. – The second dose must be given at least 1 month after the first dose. – The third dose must be given at least 2 months after the second dose and at least 4 months after the first.

How effective is twinrix after 2 doses?

Is TWINRIX 2 or 3 doses?

Standard dosing schedule consists of 3 doses (1-mL each), given intramuscularly at 0, 1, and 6 months. Alternatively, an accelerated schedule of 4 doses (1-mL each), given intramuscularly on Days 0, 7, and 21 to 30 followed by a booster dose at Month 12 may be used.